For their second full-length effort, 1999's The Cat and the Cobra, the group opted to release their album through Frenchkiss Records, an independent label formed by bassist Butler. The second album also featured a new drummer, Harrison Haynes, who replaced Mahoney. In 2000, Les Savy Fav shrunk from a quintet to a quartet with the departure of guitarist Slife, and Go Forth, released in the fall of 2001, was their first full-length effort as a four-piece, following the well-received EP Emor: Rome Upside Down. In 2004, Les Savy Fav collected a number of their small-label singles on a compilation called Inches, and they maintained an increasingly busy schedule as a live act, busy enough that it was becoming difficult for Harrington, who was raising a family with his wife, and Butler, whose Frenchkiss label was enjoying success with the Hold Steady, Passion Pit, Local Natives, and many more.
In 2005, Les Savy Fav announced they were going on an indefinite hiatus, but their sabbatical didn't last very long. By late 2006, the band reconvened to begin recording a new album, and in May 2007 they returned to the stage at the British All Tomorrow's Parties festival. Let's Stay Friends was released by Frenchkiss in the fall of 2007, and received enthusiastic reviews; it also found the band welcoming a new guitarist, Andrew Reuland, and working with a number of guest musicians, including Toko Yasuda of Enon and Blonde Redhead, Eleanor Friedberger of the Fiery Furnaces, and comedian and percussionist Fred Armisen. Les Savy Fav documented their strength as a live act with the digital-only concert LP After the Balls Drop (recorded at a New Year's Eve show that rang in 2008), and in the summer of 2010, they issued their fifth full-length studio album, Root for Ruin. ~ Mark Deming, Rovi