Garrett was born and raised in Detroit. His carpenter father also played tenor saxophone. He got his first horn as an eight-year-old and thanks to his dad's tutelage, quickly learned the G scale. While attending McKenzie High School he studied with trumpeter Marcus Belgrave and began performing with Mercer Ellington's band as a guest. He also had the good fortune to play with organist Lyman Woodard locally in Detroit. He was encouraged to begin writing his own compositions by various members of Ellington's band, and began doing so a short time later. He also played gigs with Belgrave, pianist Geri Allen, and other Detroit musicians. He won a scholarship to the Berklee College of Music in Boston, but decided to turn it down when Mercer offered him full membership in the Duke Ellington Orchestra. He remained with them for three-and-a-half years.
In 1982, he relocated to New York City, and joined the Thad Jones-Mel Lewis Orchestra. Garrett made his solo recording debut with 1984's Introducing Kenny Garrett on the Criss Cross label. During this period he also played and recorded with Art Blakey, Freddie Hubbard, and Woody Shaw. In February of 1987, Miles Davis saw a video of Garrett playing a guest spot with Dizzy Gillespie, called the saxophonist that night, and offered him a spot in his band. Garrett remained with Davis's studio and live bands through 1991.
During his tenure with the trumpeter, he signed a solo deal with Atlantic Records. He recorded two notable albums for Atlantic, Prisoner of Love and African Exchange Student in 1989 and 1990 respectively. He moved over to Warner Bros. in 1992. His label debut was the charting, critically acclaimed Black Hope. He followed up in 1995 with Triology, and recorded Pursuance: The Music of John Coltrane in 1996. He released Songbook, his first album comprised entirely of his own compositions in 1997, and followed it with Simply Said in 1999. The charting Happy People followed in 2002. Garrett concluded his tenure with the label on 2003's Standard of Language. In 2006, Garrett signed with Nonesuch. He released the Grammy-nomination for Beyond the Wall, which examined the East Asian musical tradition through modal jazz.
Two years later, he delivered Sketches of MD (recorded at N.Y.C.'s Iridium club) for Detroit's Mack Avenue label. As well as leading his own touring bands, Garrett joined the Five Peace Band's all star lineup alongside keyboardist Chick Corea, guitarist John McLaughlin, bassist Christian McBride, and drummer Vinnie Colaiuta. Five Peace Band: Live (Concord, 2009) won the Grammy for Best Jazz Instrumental Album in January 2010.
In 2012, Garrett released Seeds from the Underground his second album for Mack Ave. It featured his own group with bassist Nat Reeves, Venezuelan pianist Benito Gonzalez, and drummer Ronald Bruner Jr. The acclaimed album received Grammy nominations for Best Jazz Instrumental Album and Best Improvised Jazz Solo categories; an NAACP Image Award nomination for Outstanding Jazz Album; and a Soul Train award nomination for Best Traditional Jazz Artist/Group category. Garrett received a Jazz Awards nomination for Alto Saxophonist of the Year, and won an Echo Award for Saxophonist of the Year.
Pushing the World Away followed a year later. It featured an alternating cast of musicians --including strings -- playing mostly original compositions (and a cover of Burt Bacharach and Hal David's "I Say a Little Prayer"). It peaked at number six on the jazz charts and was nominated for two Grammy awards including Best Jazz Instrumental Album. In 2016, Garrett delivered his fourth Mack Ave. recording, Do Your Dance!, a widely varied set of originals and covers that found him exploring many varieties of dance-oriented rhythms from hip-hop and funk to Latin and Brazilian sounds.
Garrett returned to Mack Ave. for 2021's Sounds From the Ancestors. His core quintet -- pianist Vernell Brown, Jr., bassist Corcoran Holt, drummer Ronald Bruner and percussionist Rudy Bird -- was appended by a large guest list that included drummer Lenny White, pianist/ organist Johnny Mercier, conguero Pedrito Martinez, and singers Dwight Trible and Jean Baylor to name a few. Garrett explored his musical roots in Motown soul, jazz, gospel, funk, hip hop, etc. through the cornerstones of their own foundations in West African and Afro Cuban musics. ~ Thom Jurek, Richard Skelly, Rovi