Luny Tunes met while working in a dining hall at Harvard University and decided to work together as producers as well as recording and performing artists. They established their hitmaking bona fides when their track "Gasolina," one of their numerous productions from Daddy Yankee's Barrio Fino, scored global hit status in 2004. Luny Tunes also contributed productions to acclaimed albums by Don Omar (The Last Don, 2003) and Tego Calderón (El Abayarde, 2003), as well as albums by Eddie Dee (12 Discipulos, 2004), Ivy Queen (Diva, 2004), Zion Lennox (Motivando a la Yal, 2004), Nicky Jam (Vida Escante, 2004), and Trebol Clan (Los Bacatranes, 2004) -- all within a two-year span.
In 2005, Luny Tunes released Mas Flow 2, their first all-new album since the previous volume, and in 2006 they released Los Benjamins, along with a second compilation of previously released material, Reggaeton Hits, which had been preceded by a best-of collection, La Trayectoria (2004). The next mixtape dropped in 2007, Los Benjamins: La Continuacion, not long after the duo's second volume in the Kings of the Beats instrumental series. By this point, Luny Tunes were employing various assistant producers (Tainy, Jose M. Gomez, Nely, Los Presidents, Mr. G, et al.), who were employed as part of the Mas Flow Inc. production factory. Luny Tunes had established a global hitmaking rep. In 2007 they were called on to remix Janet Jackson's hit "Call on Me" (feat. Nelly). They issued the compilation Los Benjamins in 2006 and the special edition Los Benjamins: La Continuacion. This album produced the number one worldwide hit single "Noche de Entierro (Nuestro Amor)" by Daddy Yankee, Tonny Tun Tun, Hector El Father, Zion, and Wisin Yandel. "Noche de Entierro" remains one of the most famous and internationally recognized hits in reggaeton history. Luny Tunes were also employing various assistant producers and artists such as Nesty La Mente Maestra, Nely El Arma Secreta, Tainy Tunes, Anuel AA, and Nales, among others. That same year, they produced remixes for Paris Hilton ("Stars Are Blind" feat. Wisin y Yandel) and Alejandro Sanz ("Te Lo Agradezco, Pero No" feat. Shakira). In 2008, Luny Tunes signed Erre XI to their Mas Flow imprint. The duo's full-length debut, Luny Tunes Presents: Erre XI spawned the charting single "Carita Bonita" (featuring Pee Wee of Kumbia All Starz).
In 2009, the producers signed Dyland Lenny to Mas Flow and issued the smash club single "Nadie Te Amará Como Yo," followed by their participation on the Luny Tunes-produced "Rompiendo Cadenas" by Latin Grammy recording artist Ana Bárbara. In 2010 they released Dyland Lenny's debut long-player My World, which included the charting singles "Nadie Te Amará Como Yo," "Quiere Pa' Que Te Quieran," and "Caliente." Luny Tunes also worked with Ivy Queen on her seventh studio album, Drama Queen, that netted the singles "La Vida Es Así," "Cosas de la Vida," and "Aya Aya," and helmed her eighth studio album Musa in 2012.
2012 also saw the pair produce songs for Farruko's long-player album The Most Powerful Rookie and work on Daddy Yankee's Prestige, in addition to at least a dozen more.
Since 2014, the Puerto Rico-based duo concentrated their energies on production: They worked on "Adrenalina" by Wisin (feat. Jennifer Lopez and Ricky Martin); "Duele el Corazon" by Enrique Iglesias; "Mayor Que Yo 3" by Daddy Yankee, Don Omar, and Wisin Yandel; "Moviendo Caderas" by Yandel (feat. Daddy Yankee); "Limbo" by Daddy Yankee, and Latin pop tracks for Farruko, Tito el Bambino, and others. In 2018 they produced Enrique Iglesias' "El Bano" (feat. Bad Bunny). The following year they issued Mas Flow 3: Back to the Underground. ~ Jason Birchmeier, Rovi