In 2000, he formed the +2s with Moreno Veloso and Alexandre Kassin. They issued three groundbreaking albums with alternating leaders: Music Typewriter by Moreno + 2 (2000), Sincerely Hot by Domenico +2 (2003), and Futurismo by Kassin +2 (2006). He has played in and recorded with several bands including Os Ritmistas, Meia Banda, and Doces Cariocas.
In 2002 he joined Kassin's Orquestra Imperial, an 18-piece big band with the objective of re-creating the gafieira samba sound in modern compositions. They issued Carnaval Só Ano Que Vem in 2007 and remain an occasional recording and performing concern. In 2006 Lancellotti formed Os Ritmistas, a Latin-Brazilian fusion group with Danny Roland, Stephane San Juan, and Zero Awa; their self-titled debut appeared the following year. In 2008 he served as drummer/percussionist on the eponymously titled debut offering by supergroup Doces Cariocas, led by Alexia Bomtempo and Pierre Aderne. In 2009 the +2s issued their final document as a collective when they composed and recorded an original score for the dance troupe Grupo Corpo entitled Ima.
Lancellotti made his solo debut with 2011's globally acclaimed Cine Privê with assistance from Veloso, Kassin, and Money Mark, among others. With Orquestra Imperial he released Fazendo As Pazes Com O Swing the same year. He spent the next two years playing, arranging, and producing outings by Gal Costa and his former +2 bandmates. In 2013, Orquestra Imperial released the concert set Ao Vivo! In 2014, Lancellotti, Bruno di Lullo, Eduardo Manso, and Estevão Casé formed the radical Meia Banda. Their experimental self-titled debut for Rockit offered original songs threaded throughout with samba, indie pop, and neo-psychedelia and jazz. Di Lullo collaborated with Danilo Caymmi on Danilo Caymmi Canta Dorival.
In 2017 Lancellotti enlisted Sean O'Hagan (whom he'd met in London during protests against the 2012 Olympic Games) and Veloso to release the internationally acclaimed solo outing Serra Dos Órgãos (issued in the U.S. by Luaka Bop as The Good Is a Big God). He also produced Bruno Capinan's Divina Graça, and joined Gilberto Gil's road and studio bands, playing on albums such as OK OK OK and Grupo Corpo. That same year, Os Ritmistas released the album Aqui. Lancellotti and Veloso teamed to release the hit club single "Tudo Ao Redor" in 2018. In 2020 he composed and played on Marcos Valle's globally acclaimed Cinzento.
2021 proved busy for Lancellotti. Meia Banda issued the live Meia Banda no Festival Rockit! They also cut the digital EP Meio Disco with guest vocalists Moreno Veloso, Raquel Dimantas, and Taina. Lancellotti also released the solo offering Raio. Self-produced, and recorded and mixed by Daniel Carvalho, it included a studio band comprised of Continentino, Di Lullo, and guitarists Pedro Sa and Bern Gil, among others. ~ Thom Jurek, Rovi